Here goes. Finally the women get the credit they deserve.
1) Tina Fey (30 Rock, SNL)-Thank Sarah Palin for this one. See Mr. Feeny’s post on how Tina Fey became the actress of the decade.
2) Allison Janney (The West Wing)-Mr. Feeny has hit the nail on the head with this one. The reason CJ is such a compelling character on this show is that Janney portrays her with a passion that is unparalleled. CJ never hesitates to speak her mind and get involved with the issues. When something just doesn’t feel right, she lets us all know. And, she can hang with the boys like the best of ‘em. She also lets her fun and quirky side out. See this clip from season one if you doubt Janney’s versatility:

That's so Carrie
3) Sarah Jessica Parker (Sex and the City)-Are you a Carrie or a Samantha? That most people understand what this question even means is a testament to Sarah Jessica Parker’s portrayal of Carrie Bradshaw. Sex and the City aired from 1998-2004 and was capped last year by the movie. Parker’s insightful voiceovers about sex, love, men, and Manolos resonated with viewers and made the actress and the character one of the most popular of the decade.
4) Lauren Graham (Gilmore Girls)-Quirky, sarcastic, and confident, Lauren Graham’s portrayal of Lorelai in Gilmore Girls made her everything mothers could hope to be. Graham’s skill made Lorelai a down-to-earth, if totally strange, character. Her humor was one thing that did not fade throughout the seasons.
5) Sally Field (Brothers and Sisters)-I know Mr. Feeny will argue with me over this one, but I sincerely believe Sally Field is the best part of this show. Field’s portrayal of Nora Walker, the matriarch of the crazy family, really brings the whole family (nay, show) together. When her eyes glisten with love for her family, it is hard for me to believe that Sally Field is anyone but Nora Walker.

Sally Field Brings the Walkers together
Honorable Mentions
Sarah Chalke (Scrubs, How I Met your Mother)
Alyson Hanigan (Buffy the Vampire Slayer, How I Met your Mother)
Connie Britton (Friday Night Lights, The West Wing)

Farley, David Spade, Adam Sandler and Phil Hartman all make appearances. It’s kind of like the SNL-All Stars. And the essence of the Coneheads is kept intact, bringing them to a whole new audience.
3. A Night at the Roxbury — I almost gave this to the senator from Minnesota, but I couldn’t stop thinking about how unfunny this film was. I don’t think I laughed once. I never liked Chris Kattan, and there was nothing likeable about these characters. The schtick was boring at the start and just got worse. Uncool guys try to pick up women? Not the basis for an entire movie.